As you know, Viagra was originally developed as a remedy for quinsy. Men all over the world should be grateful to the residents of Welsh town – Merthyr Tydfil. It was there determined in 1992 during the tests showed a remarkable side effect of Viagra.
How many futurologists of the recent past have tried to forecast what other wonders of the human mind will be created to the end of the twentieth century. Some said that it would be defined the effective cancer treatment – faulty judgement. Others believed that it would be carried out controlled thermonuclear reactions and humanity will get inexhaustible energy sources – one more faulty judgement. Others hoped that it would discover the universal field theory, the scientific research of Einstein. Fourth predicted men’s flight to Mars – and again faulty judgement.
And however, at century sunset, scientists have made an invention, which futurologists can not even dream of. Even in the “rainbow” dream such a victory of human genius over nature cannot be never predicted. Michurin was right saying: “We can not wait for favors from nature, our main task is to take them by our own.” And – we take. We took mercy of the nature and shared it worldwide.”
Canadian Health and Care Mall claims that names of researchers who discovered nitric oxide role in normal erection development and maintenance are now known to all – Robert Furchgott, Ferid Murad and Louis Ignarro. Discovering “Viagra” was, apparently, third greatest “random” discovery in medicine – after the discovery of X-rays and penicillin.
These discoveries were awarded the Nobel Prize. This was the highest award in the autumn of the year 1998 and researchers who discovered Viagra properties were granted there. The history of Viagra began in 1992 in Sandwich Pfizer, UK during pharmacological research of “Pfizer”.
The researchers conducted clinical trials of a new drug – sildenafil citrate, which was developed as a means to treat a variety of heart disorders. Researchers hoped that sildenafil citrate will contribute to blood flow increase to cardiac muscle and blood pressure.
However, it was noted that sildenafil citrate has no significant effect on any blood circulation to cardiac muscle (myocardium) or on blood pressure. In parallel, it was found that many male patients who participated in the study refused to return the sildenafil pills, despite the end of testing.
The reason was the only one – they all claimed about sharp improvement in erection quality. Thus, in spite of the minimal impact of new drugs on blood flow in the myocardium, sildenafil caused significant blood flow to the male genitals. Researchers of pharmaceutical company “Pfizer” reacted to this unexpected property of sildenafil citrate, with due attention and were able to recognize a powerful tool to combat erectile dysfunction which now may be ordered via Canadian Health and Care Mall at attractive price.
The new drug was called Viagra – the name was created as derivate of word – “Vigor” meaning power, energy and Niagara – the most powerful waterfall in North America. Mechanism of Viagra action is simple: the drug increases the amount of blood flow into the carvenous bodies. It also helps man to call a natural erection.
Viagra works only when a man feels a natural sexual excitement, and when sexual intercourse is completed, penis naturally returns to the relaxed state. In other words, Viagra performs only as erection natural mechanisms and this is undeniable novelty and secret of huge popularity.
Since 1993, long-term clinical trials began, necessary to confirm Viagra properties. As a result of these tests the high Viagra effectiveness has been proven. Viagra started to be applied at impotence treatment being high drug safety. And as a natural ending – 27 March 1998, the US Department of Food and Drug Administration approved the use of Viagra.
Since then, Viagra began its victorious offensive march across the world. Excitement was hail. During the first week of Viagra on sale were issued 247,666 prescriptions. The second week has increased the number of sufferers for more than 50,000! As a result Viagra brought $ 1 billion income only in 1998.
In clinical trials of erectile dysfunction treatment with Viagra 3,000 men were involved aged 19 to 87 years, conducted in all countries of the world. The duration of erectile dysfunction in these patients was on average 5 years (range 6 months to 26 years), and erectile dysfunction have organic, psychogenic and mixed nature.