With the recent buzz about Maria Sharapova and Mildronate, Canadian Health and Care Mall throw some light on the drug, otherwise known as Meldonium. Meldonium/Mildronate is a drug with its origins in the European country of Latvia. It is known to be in existence since the 1970s, when a chemist in Latvia happened to chance upon its discovery. As a result, it is sold as an over-the-counter drug in Russia, Ukraine and parts of Europe (such as Eastern Europe and the Baltic countries). It is used in the treatment of certain cases of heart problems.
What is Meldonium?
Meldonium is a drug or a prescribed medication for the treatment of Ischaemia. It is the condition in which there occurs a lack of blood flow to certain parts of the body. It is especially prescribed to treat heart failure or angina.
What Does It Do To The Body?
Meldonium is typically known to increase blood flow in the body and provide an oxygen boost. This in turn improves the exercise capacity of the person. Canadian Health&Care Mall says that it is a hormone and a metabolic modulator and hence has been classified as an S4 substance under Wada code.
In the scientific language, Meldonium/Midronate is known as Mildronate (3-(2,2,2-Trimethylhydrazinium)propionate with the chemical formula C6-H14-N2-O2 and molecular weight of 146. It is an antiischemic drug which was developed and designed in order to inhibit the process of carnitine biosynthesis. It is a natural process that requires/demands high amounts of oxygen so as to function. Apart from treating cardiac ischemia and its consequences, it is also found to have a considerable effect on the Central Nervous System (CNS) in a way that it helps improve the mood or feeling of the patient. It also reduces motor dysfunction faced by some of the patients prescribed to it. As a result, the dizziness and nausea linked to it reduce as well.
Canadian Health&Care Mall survey shows that Meldonium is popular amongst the sports persons as it is known to increase their endurance and boost performance in sports, especially that of the athletes. It also facilitates quick recovery after exercising and reduces stress in addition to enhancing the central nervous system’s activities.
Meldonium is found to inhibit the substance I-carnitine found in the body. I-carnitine is responsible for carrying the trans-fats to the mitochondria in the cell, which is then burnt there to release energy for the body’s consumption. When this I-carnitine is blocked by Meldonium, it results in glucose being carried to the cell and burned instead to release energy. Now burning of glucose in order to release energy is a process that requires lesser amount of oxygen as compared to burning of trans-fats. Thus, this process leaves more amount of oxygen in the body to be utilized for other processes. In other words, we say it reduces oxidative stress and cellular damage and in turn, helps the body to consume energy more efficiently.
More Information Awaited
Over and above all the claims made above, Canadian Health&Care Mall clarify that Meldonium is still to be tested rigorously for further actions on the human body. A large number of the effects were concluded from the experiments carried out on rodents and a few more on humans directly. Although no strong comments can be made for and/or against Meldonium, it is known to have significant positive aspects which have made it a popular choice amongst the athletes and other sports persons.